Johann Nepomuk Czermak and his isolated frog heart

Isolated Frog Nerve Fiber

T HAS BEEN SHOWN that the myelin sheath and the surface membrane at the node of Ranvier of the myelinated nerve fiber behave, to a weak penetrating current, like a condenser with an ohmic resistance connected in parallel (1–5). The absolute values of these capacities and resistances have been estimated already with some accuracy. In order to analyze the process of action potential production at...

The unsolved mystery of Johann Georg Wirsung and of (his?) pancreatic duct.

MANY CENTURIES have passed, and much has been written about the controversial discovery of the pancreatic duct by Johann Georg Wirsung. His brutal death was even more mysterious, the truth being almost certainly blown away in the alleys of Renaissance Padua. In November 1629, after studying anatomy in Paris and Altdorf, the German student Johann Georg Wirsung moved to Padua, where he graduated ...

Effect of aqueous extract of Ipomoea carnea leaf on isolated frog and mouse heart.

Ipomoea carnea fam. Convolvulaceae is a poisonous plant and its toxicity is supposed to be due to the cardiac and respiratory failure. The present paper describes the cardiac effect of aqueous extract of the fresh leaves of I. carnea using mouse and frog heart. The aqueous extract produced an initial blockade of isolated frog heart for 5-10 sec followed by dose dependent increase in both amplit...

The action of iodoacetate on the electrical and mechanical activities of the isolated perfused frog heart.

John gibbon and his heart-lung machine.

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